Hereditary Cancer

A study of 592,158 men put HOXB13 G84E at a hazard ratio of 3.17. Here is what that means in absolute numbers, and what it means for screening, family and insurance.

A BLM carrier flag is not Bloom syndrome: the inheritance math, the registry cancer numbers, testing routes in the US and Canada, and what GINA leaves out.

A FANCC carrier flag is not a diagnosis. A research-grounded guide to Fanconi anemia group C: per-pregnancy odds, testing, cancer risk, and 2026 treatments.

MUTYH-associated polyposis is an inherited colon-cancer syndrome. Learn what biallelic vs monoallelic risk really means, how a 23andMe result differs from clinical testing, and your GINA rights.

A BRCA1 or BRCA2 mutation raises cancer risk well above average, but it is not a guarantee. Here is what the research shows, in plain numbers.