Neurogenetic Diseases

A research-grounded guide to an SMN1 carrier result for spinal muscular atrophy: what one variant means in pregnancy, the real recurrence-risk math, US and Canada testing, and honest treatment status.

A research-grounded guide to a HEXA carrier result for Tay-Sachs: what one variant means, the real recurrence-risk math, US and Canada testing, and honest treatment status.

A LRRK2 or GBA variant raises Parkinson's risk, but most carriers never develop the disease. Here is what the research shows, in plain numbers.

APOE ε4 is the strongest genetic risk factor for late-onset Alzheimer's, but it is not destiny. Here is what research shows about one vs two copies, what testing means, how new drugs relate to ε4, and what you can actually do.