Metabolic and Hematologic Genetic Diseases

Are kidney stones genetic? Twin, family and gene studies in plain English, what a 23andMe score means, warning signs, and prevention backed by trials.

Most high triglycerides come from many small gene effects plus lifestyle, not one gene. Learn the numbers, pancreatitis risk, testing and new drugs.

A study of 1,028,980 adults mapped blood pressure genetics in detail. Here is what a polygenic risk report can tell you, and what only a cuff can.

Polygenic gallstone risk, explained: what the 2025 71,384-case study found, why an ultrasound beats a DNA kit, and what the odds mean out of 100.

A genetic risk score for coronary artery disease shifts your odds, not your fate. Here is what the research shows, in plain out-of-100 numbers.

Gout needs two inherited systems to fail, not just uric acid. What ABCG2, SLC2A9 and a genome-wide study of 2.6 million people actually show.

A consumer type 2 diabetes score is a population probability, not a diagnosis. What 611 loci, the DPP trial and US and Canadian rules actually say.

An FAH carrier flag is not a diagnosis. A research-grounded guide to tyrosinemia type I: the inheritance math, testing in the US and Canada, and nitisinone.

A DTC report flagged your Prothrombin G20210A variant? A research-grounded look at what your roughly 3-4x clot risk means in absolute terms, plus testing, GINA, and family guidance.

A carrier line on a 23andMe report is not a diagnosis. Grounded in the first 2024 HFI clinical guidelines, StatPearls, and NIH, here is what ALDOB carrier status means for you and your family.